概述
接口通过公司名称获取数据详细信息,目前收录了103,992条数据信息。数据收集了全球医疗及相关领域的交易事件,通过对信息和数据的生产、聚合、挖掘、加工、处理,帮助目标用户和客户节约时间和金钱、提高效率,以辅助其各类商业行为,包括风险投资、收购、竞争情报、BD交易、国外公司产品信息数据服务等。
数据结构
{
"title": "交易标题",
"abstract": "交易摘要",
"case_theme": ["事件主题"],
"case_type": ["事件类型"],
"date_bgn": "交易开始日期",
"date_end": "交易结束日期",
"update_time": "最近更新日期",
"trading_status": "交易状态",
"include_territories": ["许可地区"],
"exclude_territories": ["排除地区"],
"if_inoption": "是否含权",
"if_disclose": "是否披露财务信息",
#交易参与方信息
"principal_entity": {
"entity_name": "企业名称",
"entity_location": {
"country": "国家",
"region": "地区",
"address": "地址",
},
}, # 主要参与方/标的持有方
"partner_entity": {
"entity_name": "企业名称",
"entity_location": {
"country": "国家",
"region": "地区",
"address": "地址",
},
}, # 其他参与方
#交易财务详情
"tot_project": {
"amount_num": "数量",
"currency": "货币种类",
"magnitude": "数量级",
}, # 预计总金额
"tot_paid": {
"amount_num": "数量",
"currency": "货币种类",
"magnitude": "数量级",
}, # 已付总金额
"detail_payment": [{
"payment_type": "支付类型",
"payment_amount": "金额",
"payment_notes": "说明",
}], # 支付详情-预计金额
"detail_paid": [{
"paid_date": "支付日期",
"paid_type": "支付类型",
"paid_amount": "金额",
}], # 支付详情-已付总金额
#交易涉及药物信息
"drug": [{
"trade_status": "交易时研发阶段",
"drug_name": "药物名称",
}],
"drug_type": ["药物类型"],
"target": ["靶点"],
"indication": ["适应症"],
"therapy_area": "治疗领域",
"tech":"药物设计技术",
#交易进展-事件
"time_line": [{
"event_date": "事件日期",
"event_type": "事件类型",
"description": ["事件描述"],
"news_url": ["资讯链接"],
"event_drug": ["事件相关药物"],
"stage": ["事件涉及临床阶段"],
"if_disclose": "事件是否更新财务信息",
"financial": {
"payment_type": "支付类型",
"value": "金额-百万美元",
"num": "金额数值"
} # 事件披露财务信息
}]
}
数据样例
{
"title": "AbbVie Inc将全球开发和商业化北京加科思新药研发有限公司(Jacobio Pharmaceuticals Co Ltd)的SHP2抑制剂JAB-3068和JAB-3312用于癌症治疗,并拥有选择权",
"abstract": "2020年5月,AbbVie Inc签署了一项独家全球战略合作协议,以开发和商业化北京加科思新药研发有限公司(Jacobio Pharmaceuticals Co Ltd)的SHP2抑制剂JAB-3068和JAB-3312用于癌症治疗。该交易需根据Hart-Scott-Rodino反垄断改进法案获得批准。2020年9月,北京加科思新药研发有限公司行使了中国选项,并授予AbbVie Inc全球独家分许可,以研究、开发、制造、商业化并其他方式使用其SHP2抑制剂,包括JAB-3068和JAB-3312用于癌症治疗。2021年6月,北京加科思新药研发有限公司触发了AbbVie Inc的里程碑支付,因为JAB-3312与Pembrolizumab和Binimetinib在I/IIa期临床试验中的给药。2023年7月,北京加科思新药研发有限公司宣布终止与AbbVie Inc的许可和合作协议,并将重新获得包括JAB-3312在内的SHP2抑制剂的全球开发和商业化权利,因为无法保证成功开发和商业化。",
"case_theme": [
"药物开发"
],
"case_type": [
"含权交易",
"合作协议",
"授权许可",
"国内to国外",
"跨国交易"
],
"date_bgn": "2020-05-29",
"date_end": "2023-07-04",
"update_time": "2023-07-04",
"trading_status": "终止",
"include_territories": ["全球"],
"exclude_territories": [],
"if_inoption": "否",
"if_disclose": "披露金额",
"principal_entity": {
"entity_name": "北京加科思新药研发有限公司",
"entity_location": {
"country": "中国",
"region": "北京",
"address": "北京市北京经济技术开发区经海三路105号院8号楼"
}
},
"partner_entity": {
"entity_name": "AbbVie Inc",
"entity_location": {
"country": "美国",
"region": "",
"address": "1 North Waukegan Road North Chicago Illinois 60064-6400"
}
},
"tot_project": {
"amount_num": 855,
"currency": "美元",
"magnitude": "百万"
},
"tot_paid": {
"amount_num": 65,
"currency": "美元",
"magnitude": "百万"
},
"detail_payment": [
{
"payment_type": "里程碑",
"payment_amount": "810.00",
"payment_notes": ""
},
{
"payment_type": "研发资金募集",
"payment_amount": "Payment Unspecified",
"payment_notes": "Undisclosed R&D fund"
},
{
"payment_type": "首付",
"payment_amount": "=45.00",
"payment_notes": "non-refundable pre-agreed upfront payment of $45 million"
}
],
"detail_paid": [
{
"paid_date": "2020-09-04",
"paid_type": "首付",
"paid_amount": "=45.00"
},
{
"paid_date": "2021-06-10",
"paid_type": "里程碑",
"paid_amount": "20.00"
}
],
"drug": [
{
"drug_name": "JAB-3068",
"trade_status": "Ⅰ期临床"
},
{
"drug_name": "JAB-3312",
"trade_status": "Ⅰ期临床"
}
],
"drug_type": ["化学药"],
"target": ["KRAS", "SHP2", "MAPK"],
"indication": ["实体瘤"],
"therapy_area": ["肿瘤", "癌症"],
"tech": [],
"time_line": [
{
"event_date": "2023-07-04",
"event_type": "交易终止",
"description": [
"2023年7月,北京加科思新药研发有限公司(Jacobio Pharmaceuticals Co Ltd)宣布终止与AbbVie Inc的许可和合作协议,并将重新获得包括JAB-3312在内的SHP2抑制剂的全球开发和商业化权利,因为无法保证成功开发和商业化。",
"双方将合作有序过渡责任,过渡期不超过180天。",
"在过渡期内,AbbVie Inc将继续报销所有预批准开发计划下的成本。"
],
"news_url": [
"https://in.marketscreener.com/quote/stock/JACOBIO-PHARMACEUTICALS-G-119080147/news/Jacobio-Pharmaceuticals-Group-Co-Ltd-announced-that-it-expects-to-receive-CNY-150-million-in-fund-44284969/"
],
"event_drug": ["JAB-3312"],
"stage": [],
"if_disclose": "未披露",
"financial": []
},
{
"event_date": "2021-06-10",
"event_type": "开发里程碑",
"description": [
"2021年6月,北京加科思新药研发有限公司(Jacobio Pharmaceuticals Co Ltd)触发了AbbVie Inc的2000万美元里程碑支付,因为JAB-3312与Pembrolizumab和Binimetinib在I/IIa期临床试验中的给药。",
"这一临床里程碑将为后续药物组合的研究和开发提供财务支持并注入信心。"
],
"news_url": [
"http://www.prnewswire.com/news-releases/jacobio-announces-first-two-patients-dosed-in-shp2-combination-study-triggering-us20-million-milestone-payment-301314880.html"
],
"event_drug": [
"JAB-3312"
],
"stage": [],
"if_disclose": "披露金额",
"financial": [
{
"payment_type": "研发/注册里程碑",
"value": "USD = 20.00 M",
"num": 20
}
]
},
{
"event_date": "2020-09-04",
"event_type": "期权执行",
"description": [
"2020年9月,北京加科思新药研发有限公司(Jacobio Pharmaceuticals Co Ltd)行使了中国选项,并授予AbbVie Inc全球独家分许可,以研究、开发、制造、商业化并其他方式使用其SHP2抑制剂,包括JAB-3068和JAB-3312用于癌症治疗。",
"北京加科思新药研发有限公司将继续与AbbVie Inc进行JAB-3068和JAB-3312的早期全球临床试验,并承担注册试验前的研发费用。",
"早期试验完成后,AbbVie Inc将在全球(除领土外)承担这两个候选药物的开发和商业化责任。",
"北京加科思新药研发有限公司将收到4500万美元的不可退还预付款。",
"AbbVie Inc将支付高达8.1亿美元的开发、商业化和销售里程碑付款,其中包括高达3.1亿美元的开发里程碑,高达1.5亿美元的某些司法管辖区的首次商业销售,以及高达3.5亿美元的商业销售目标达成时支付。",
"AbbVie Inc将支付低至中双位数百分比的版税。",
"从AbbVie Inc收到的不可退还预付款不受任何进一步条件的约束。"
],
"news_url": [],
"event_drug": [
"JAB-3068",
"JAB-3312"
],
"stage": [],
"if_disclose": "披露金额",
"financial": [
{
"payment_type": "首付款",
"value": "USD = 45.00 M",
"num": 45
}
]
},
{
"event_date": "2020-05-29",
"event_type": "原始交易",
"description": [
"2020年5月,AbbVie Inc签署了一项独家全球战略合作协议,以开发和商业化北京加科思新药研发有限公司(Jacobio Pharmaceuticals Co Ltd)的SHP2抑制剂JAB-3068和JAB-3312用于癌症治疗。",
"JAB-3068和JAB-3312是SHP2(PTPN11)抑制剂,通过阻断Kirsten大鼠肉瘤病毒癌基因同源物(KRAS)-丝裂原活化蛋白激酶(MAPK)信号通路,减少癌细胞生长并调节免疫反应,目前处于I期。",
"JAB-3068和JAB-3312的早期全球临床试验将由北京加科思新药研发有限公司与AbbVie Inc共同进行,AbbVie Inc承担研发费用。",
"AbbVie Inc将负责全球开发和商业化。",
"北京加科思新药研发有限公司将拥有在注册试验开始前行使开发和商业化SHP2项目的选择权,仅限于中国大陆、香港和澳门。",
"财务条款未披露。",
"该交易需根据Hart-Scott-Rodino反垄断改进法案获得批准。"
],
"news_url": [
"http://www.prnewswire.com/news-releases/jacobio-announces-first-two-patients-dosed-in-shp2-combination-study-triggering-us20-million-milestone-payment-301314880.html",
],
"event_drug": [
"JAB-3068",
"JAB-3312"
],
"stage": [],
"if_disclose": "未披露",
"financial": []
}
]
}